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Gastro-intestinal

BHR markets three tests that can alter the outcome of disease progression by helping to catch these diseases early in their development.

These are the actimFECALBLOOD test to detect colonic cancer, the actimPANCREATITIS test which detects cases of acute pancreatitis, and finally, Medi-Test Combi-10 which detects blood, protein, nitrite and leukocytes in urine.


Fecal Occult Blood

Colorectal cancer affects men and women equally and is one of the leading types of cancer. Occult blood in fecal samples is a sign of bleeding in the gastrointestinal tract. As tumors bleed, its presence may therefore indicate colorectal cancer.

ActimFECALBLOOD is an immunochromatographic test based on monoclonal antibodies detecting hemoglobin in fecal samples.

The test is easy and hygienic to use and being specific for human hemoglobin requires no patient dietary restrictions.

The test sensitivity is set to detect patients having more than 25-50 µg hemoglobin per gram of feces and needing subsequent endoscopic examinations


Pancreatitis

The pancreas is a gland which lies in the back of the upper abdominal cavity. The gland has two main functions. It produces an enzyme to help digest certain types of food in the gut, particularly fats. The second is to produce the hormone insulin which controls the level of glucose in the body cells.

Pancreatitis results from partial damage to the pancreas itself by its own enzymes. As a result of this, severe abdominal pain and vomiting may result.

The chronic inflammation of the pancreas gland often produces pain in the upper abdomen and back. Acute pancreatitis is a serious disease in which 20-30% of patients may develop severe pancreatitis with up to 40% mortality. As treatment is more likely to succeed if initiated early, rapid diagnosis of acute pancreatitis is vital.

Acute pancreatitis usually occurs either in patients with gallstones, or those who drink excessive amounts of alcohol. Rarely it can be a result of direct injury, or occur in patients with abnormal amounts of fat (cholesterol and similar chemicals) in the blood. It can also be a consequence of other infections.

Further attacks of pancreatitis may occur unless the underlying cause is treated. In such repeated or bad attacks, the pancreas may be severely damaged and permanent diabetes may result.

Currently, the “gold standard” test is the amylase test. ActimPANCREATITIS has better specificity.

ActimPANCREATITIS is an immunochromatographic dipstick test based on monoclonal antibodies detecting trypsinogen-2 from urine. Trypsinogen-2 is a more reliable marker for acute pancreatitis than amylase as its levels stay elevated for days or even weeks, while amylase levels start to decline after 1-3 days.

This specific and sensitive test can rule out acute pancreatitis with at least 99% certainty, thus allowing patients with other conditions to be correctly diagnosed sooner.


Medi-Test Combi-10 SGL

These tests are used for rapid determination of blood, urobilinogen, bilirubin, protein, nitrite, ketones, glucose, pH-value, density and leukocytes in urine for:

1. screening test for detection of diabetes, metabolic abnormalities

2. liver diseases

3. biliary and hepatic obstructions

4. hemolytic diseases

5. diseases of kidney and urinary tract

BHR Pharmaceuticals Ltd
41, Centenary Business Centre, Hammond Close, Nuneaton, Warwickshire CV11 6RY
: t : +44 (0) 870 0349 606 : : f : +44 (0) 870 0349 607 : : e : info@bhr.co.uk :