Why RAMP?

•  Multi-port reader
•  High throughput of 18-36 tests/hour (3 module unit)
•  Touch-screen interface
•  Temperature-controlled ports
•  Backwards compatible for all analytes
•  Additional software features for customization and compliance
•  Enhanced data management
•  Increeased connectivity
•  Multi-language compatible
•  Internal electronic QC (IQC) and external liquid QC (IQC) available
•  No calibration required
•  Printer and scanner also available

How the RAMP® System Works

Each disposable, single-use Test Cartridge houses an analyte-specific, immunochromatographic strip on which the Assay runs. The RAMPR System uses an internal calibrator incorporated into each test strip to compensate for test-to-test variations.

To perform an assay, the operator transfers a sample into the sample well of a cartridge and inserts the cartridge into the Reader. The sample is drawn by capillary action along the membrane. Analyte present in the sample interacts and binds with the fluorescently-labeled antibodies forming an antibody-antigen complex. The complexes and labeled antibodies are subsequently captured at the detection and internal standard zones. When the reaction in the cartridge is complete, the Reader scans the assay strip and detects fluorescence in the detection and the internal standard zones, then by comparing fluorescence captured at the detection and internal standard zones, converts this ratio

(RAMP® Ratio) into an analyte concentration using lot-specific calibration data. The use of the RAMP® Ratio significantly reduces variation due to sample, operator and membrane differences. The assay result is displayed on the Reader’s LCD (liquid crystal display) following test development. The result is stored and can be printed, uploaded to a PC, or deleted.

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RAMP Specification

Weight
2.0kg (4.4lbs) for each Control Module and Test Module

Dimensions
20cm wide x 19.5cm deep x 10.5cm high
(7.87″ wide x 7.68″ deep x 4.13″ high

Power Requirements
Universal power supply

Transformer
Transformer output power 12 VDC

External Connections
LAN
USB (3 ports)
Custom DIN connectors for Test Modules (3 ports)

Keypad
Touch-sensitive VGA display with full alphanumeric keyboard
Options for custom characters and menu displays

Display
Full VGA colour

Test Principle

1. Specific antibodies attached to flourescent-dyed latex particles bind to the analyte of interest
2. The fluid sample is then transported through the strip by capillary action
3. Detection Zone: Latex particles bound to analyte are captured
4. Internal Standard Zone: Unbound latex is captured and used as an internal calibrator

The RAMP Ratio

RAMP measures flourescence at the Detection and Internal Standard Zones. Replicates of standards tested in the RAMP Assay show that even extreme differences at the Detection Zone can be corected by use of the RAMP Ratio. Replicates with higher levels at the Detection Zone also show higher levels of flourescence measured at the Internal Standard Zone. The RAMP Ratio calculated between these two zones corrects for test-to-test variations. Without the Ratio, flourescence at the Detection Zone would be measured alone, leading to extrememly variable results. This makes RAMP more accurate than other tests.

FAQs

BHR are here to help, and we welcome any feedback on any of our products. Should you have any questions regarding this, or any other product, please get in touch with us by email here and we’ll get right back to you and post all relevant questions on this page.